All HPLC separations run better in an optimized climate and
sometimes they won't even run without. Many chiral separations
require sub-ambient temperatures for sufficient resolution and
many ion-exchange separations are efficient only at elevated
temperatures. Every separation is a function of temperature
and stable retention times can only be guaranteed if the
column temperature is not influenced by ambient temperature
fluctuations. Obviously, temperature control will also help to
comply with GLP requirements. Column back-pressure reduction
may be needed if you want to speed up your HPLC analysis and a
simple increase in temperature will do the job. The Mistral
column thermostat offers precise and stable temperature
control ranging from 5 oC up to 90 oC to bring even your most
demanding separation under control. The forced-air concept
allows easy access to the column(s) and offers maximum
flexibility with respect to column dimensions. So, remember
Mistral, when your column needs a change of climate.